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Small nerve fibres detected
in the functional layer in all women with endometriosis
may have important implications for understanding
the generation of pain in these patients. The presence
of nerve fibres in an endometrial biopsy may be
a novel surrogate marker of clinical endometriosis.
Tokushige
N, Markham R, Russell P, Fraser IS. High density
of small nerve fibres in the functional layer of
the endometrium in women with endometriosis. Human
Reprod 2006; 21(3): 782-787.
A Cochrane review has found that
endometriosis patients who use gonadotropin-releasing
hormone (GnRH) agonists in the run-up to IVF have
improved outcomes.
Sallam
HN, Garcia-Velasco JA, Dias S, Arici A. Long-term
pituitary down-regulation before in vitro fertilization
(IVF) for women with endometriosis. Cochrane Database
of Systematic Reviews 2006; 1.
The proliferative activity of early
ovarian clear cell adenocarcinoma seems to depend
on the association of this cancer with endometriosis.
When endometriosis is associated with ovarian clear
cell adenocarcinoma, there is a change of its cytokine
production that may inhibit tumour growth.
Komiyama
SI, Aoki D, Katsuki Y, Nozawa S.Proliferative activity
of early ovarian clear cell adenocarcinoma depends
on association with endometriosis. Eur J Obstet
Gynecol Reprod Biol 2006.
Expression of class I human leukocyte
antigen (HLA I) is significantly higher in endometrial
samples from patients with endometriosis than in
those from other people.
Vernet-Tomas
del M, Perez-Ares CT, Verdu N, Molinero JL, Fernandez-Figueras
MT, Carreras R. The endometria of patients with
endometriosis show higher expression of class I
human leukocyte antigen than the endometria of healthy
women. Fertility and Sterility 2006; 85: 78-83.
Women with a specific type of uterine
anomaly appear to be at high risk of endometriosis,
even though their menstrual flow is not obstructed,
researchers report.
Nawroth
F, Nawroth F, Rahimi G, Nawroth C, Foth D, Ludwig
M, Schmidt T. Is there an association between septate
uterus and endometriosis? Hum Reprod. 2006; 21(2):
542-4.
A low-dose norethindrone
acetate could be considered an effective, tolerable,
and inexpensive first-choice medical alternative
to repeat surgery for treating symptomatic rectovaginal
endometrioti lesions in patients who do not seek
conception.
Vercellini
P. Pietropaolo G, De Giorgi O, Pasin R, Chiodini
A, Crosginani PG. Treatment of symptomatic rectovaginal
endometriosis with an estrogen-progestogen combination
versus low-dose norethindrone acetate. Fertil Steril
2005; 84(5):1375-87.
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